There are four characters appearing in ASCII and Unicode which look like combining marks but are actually base characters.  (The four characters and their code points are:  circumflex accent (5E(hex)), low line (5F(hex)), grave accent (60(hex)), tilde 7E(hex)).  MARC 21 records do not use these four code points as combining characters.  Equivalent combining characters are represented by other code points in either encoding.

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Part 1:  General Character Set Issues

Character Sets and Encoding Options